Connected Portals
The NIH Common Fund-supported program aims to “accelerate research and promote discoveries for children affected with cancer and structural birth defects”. Currently the DRC contains data from over 34,000 participants, including DNA and RNA.
“The goal of the National Institutes of Health (NIH) INCLUDE Project is to improve the health and quality of life for people with Down syndrome (DS). INCLUDE stands for INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE. People with Down syndrome develop certain medical conditions, like Alzheimer’s disease and autoimmune conditions, more often than the general population, yet they seem to be protected from some cancers and other common co-occurring conditions. In 2018, the NIH launched the INCLUDE Project to help understand why.” INCLUDE contains a variety of data types from over 9,000 participants.
Exceptional longevity (EL) is an extreme phenotype representing the ability to achieve exceptional health span. EL may be influenced by differing domain-specific factors that affect preserved performance in physiologic systems (e.g., respiratory, cardiovascular, immune) or functional domains (e.g., mobility, cognition). Understanding the functional effects of protective human genetic variants and cellular factors associated with EL could help identify novel targets for interventions to mimic their favorable effects.
The AD Knowledge Portal allows researchers to discover and download Alzheimer's Disease data, analyses, and tools from the National Institute on Aging's Alzheimer's Disease Translational Research Program.
NF Portal (Synapse)
The NF Data Portal was created to help openly explore and share NF datasets, analysis tools, resources, and publications related to neurofibromatosis and schwannomatosis. Anyone can join the NF Open Science Initiative (NF-OSI) to contribute!
Gen3 BioData Catalyst serves as the data portal for the NHLBI BDC ecosystem. It includes datasets from TOPMed, CHS, FHS, and others. Data is also discoverable, with a different interface, directly through the BioData Catalyst powered by Seven Bridges platform.
The CGC is an NCI dedicated platform and allows discoverability of data from the Cancer Research Data Commons. More information about datasets on the CGC can be found here: https://www.cancergenomicscloud.org/datasets
SRA (via SRA to DRS converter)
Unlocks the wealth of data house in the Sequence Read Archive.
Blog: https://velsera.com/unlocking-genomic-discoveries-seamless-access-to-the-sequence-read-archive
